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Dr Harvey Roweth

Harvey Roweth
  • Lecturer in Cancer Biology
  • Admissions Tutor for BSc. Medical Science

Areas of interest

  • The roles of platelets in promoting tumour angiogenesis and metastasis.
  • Predicting and understanding cancer-associated thrombosis.
  • Ex vivo modelling and targeting of circulating tumour cells.

Teaching

  • Part 1: Human Pathology
  • Part 4: Project Planning, Laboratory Skills, and Experimental Design

Awards and honours

Research funding

  • National Cancer Institute, K99/R00 Pathway to Independence Award, USA, 2023. $1,102,068 (PI).
  • Discover Brigham. Microgrant, USA, 2023. $1,500 (PI).

Local collaborators

  • Professor Jon Gibbins, School of Biological Sciences
  • Professor Phil Dash, School of Biological Sciences
  • Dr. Craig Hughes, School of Biological Sciences
  • Dr. Mike Fry, School of Biological Sciences

(Inter)national collaborators

  • Dr. Elisabeth Battinelli, Brigham and Women’s Hospital, Boston, USA
  • Dr. Sandra McAllister, Brigham and Women’s Hospital, Boston, USA
  • Dr. Joseph Italiano, Boston Children’s Hospital, Boston, USA
  • Dr. Alec Schmaier, Beth Isreal Deaconess Medical Centre, Boston, USA
  • Dr Bethan Psaila, University of Oxford, UK
  • Dr. Isabelle Becker, Queen Mary University of London, UK

Esteem factors

  • Scientific Committee on Megakaryocytes and Platelets, American Society of Hematology (2024-2028)
  • Thrombosis and Hemostasis Working Group. American Society of Hematology (2025-2027).
  • Abstract reviewer. American Society of Hematology Annual Meeting (2022-2024).
  • BWH Research Performance Incentive Program (2023).
  • Eberhard F. Mammen Young Investigator Award (2023).
  • Early Career Travel Award, International Society on Thrombosis and Haemostasis (2022).
  • Poster Award, Megakaryocytes and Platelets Gordon Research Seminar (2017, 2019).
  • Avrith Travel Award, University of Cambridge (2017).
  • Travel Award, British Society for Haemostasis and Thrombosis (2017).

Scientific peer review

  • Ad-Hoc reviewer for Arteriosclerosis Thrombosis and Vascular Biology (ATVB), Cell Biology and Toxicology, eBioMedicine, International Journal of Molecular Sciences (IJMS), Journal of the American College of Cardiology Basic to Translational Science (JACC BTS), Journal of Thrombosis and Haemostasis (JTH), Molecular Cancer, Pharmaceuticals, Platelets, Research and Practice in Thrombosis and Haemostasis (RPTH), Scientific Reports, Thrombosis Research, Transfusion.
  • preLights contributor for The Company of Biologists.
  • Review Panel, Hemostasis & Thrombosis Research Society Seed Grants (2025).
  • Principal Editor, Platelets (2024-2028).
  • Review Editor, Frontiers in Cardiovascular Research (2024 - current).

Selected publications

Please follow this  for a complete list of published work.

  • Roweth HG, Becker IC, Malloy MW, Clarke EM, Munn S, Kumar PL, Aivasovsky I, Tray K, Schmaier AA, Battinelli EM. Platelet angiopoietin-1 protects against murine models of tumor metastasis. ATVB. 2024, Sep;44(9):2024-2037.

     

  • Roweth HG, Platelet Contributions to the (Pre)metastatic Tumor Microenvironment. Semin Thromb Hemost, 2024 Apr;50(3):455-461. 

     

  • Guo Q, MalloyMW, Roweth HG, McAllisterSS, Italiano JE, BattinelliEM. Platelets upregulate tumor programmed death-ligand 1 in an epidermal growth factor receptor-dependent manner in vitro. Blood Adv. 2022 Oct 25;6(20):5668-5676.

     

  • Roweth HG, MalloyMW, GorecznyGJ, BeckerIC, GuoQ, Mittendorf EA, Italiano JE, McAllisterSS, and BattinelliEM. Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer. Sci. Adv. 2022 Oct 14;8(41). 

     

  • Roweth HG and Battinelli EM, Lessons to Learn from Tumor-Educated Platelets. Blood. 2021 Jun 10;137(23):3174-3180.

     

  • Faria do Valle I, Roweth HG, Malloy MW, Moco S, Barron D, Battinelli EM, Loscalzo J, Barabasi A-L. Network Medicine Framework Shows Proximity of Polyphenol Targets and Disease Proteins is Predictive of the Therapeutic Effects of Polyphenols. 2020. Nature Food 2; 143-155.

     

  • Johnson KE, Ceglowski JR, Roweth HG, Forward JA, Tippy MD, El-Husayni S, Kulenthirarajan R, Malloy MW, Machlus KR, Chen WY, Italiano JE Jr, Battinelli EM. Aspirin inhibits platelets from reprogramming breast tumor cells and promoting metastasis. Blood Advances. 2019 Jan 22;3(2):198-211.

     

  • Roweth HG, Yan R, Bedwani NH, Chauhan A, Fowler N, Watson AH, Malcor JD, Sage SO, Jarvis GE. Citalopram inhibits platelet function independently of SERT-mediated 5-HT transport. Sci. Rep. 2018. Feb 22;8(1):3494.

Publications

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